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deuce222
Registered User
(10/31/09 6:59 pm)


Do NSAIDS help ?

I have recurrent pars planitis and I was looking at the treatment algorythm for it provided by Dr. Foster.
My doctor talked about Immunosupressive drugs I may need to start.I noticed other doctors in various peoples posts going on to these drugs. I was wondering about these Nsaid drugs myself Because they are familiar to me. I have taken them before. I wonder why do Drs skip that step, Do NSAIDS work?
thanks for any input
Frank

Webmaster
Administrator
(10/31/09 9:59 pm)


Re: Do NSAIDS help ?
Hi Frank,

For other's to read: This is the treatment strategy for Parsplanitis advocated by the Ocular Immunology and Uveitis Foundation that Frank mentions.

Up to six steroid injections, separated by several weeks each, are the first step. If there is not improvement early on in this therapy, Dr. Fister adds NSAID to the recipe (injections + NSAID).

If the combination NSAID and regional injecitons don't get the job done, of if the injections cause complications such as high intraocular pressures, then surgery or imunomodulatory therapies are available alone or in combination and are very effective.

Not all physicians think alike with regard to the usefulness of NSAID trial. Each case should be considered individually. If you want to try NSAID along with injections, ask your physician about his or her experience with this. You probalby won't get much resistance to adding them. If you need to move on the IMT or surgery, NSAID is probably not in your future as a cure.

All of my best,

Liz

Edited by: Webmaster at: 10/31/09 10:08 pm
bshimada
Registered User
(11/2/09 9:10 am)


NSAIDs
Hi Frank-

I have anterior uveitis, not pars planitis, so I know my experience may not be relevant to yours. NSAIDs have been able to control my uveitis, and may have put me in remission (fingers crossed, say a prayer, put out the prayer flags....)

I agree with Liz, though, your docs probably will be willing to give it a try. One of my ophthalmologists, who was skeptical if it would work, said, "Well, you probably won't do yourself any harm, so if you want to try it, I won't object." Not exactly a resounding endorsement but at least she didn't stand in my way.

Hope you find relief soon.

Beverly

MikeBartolatz
Registered User
(11/2/09 9:48 am)


Re: NSAIDs
Vitrectomy with pars plana endolaser seems to work the best in getting pars planitis patients to remission. a combination of methotrexate and cyclosporin occasionally works as well for pars planitis patients. Cellcept in place of methotrexate also works sometimes. I don't recall of anyone posting to the sites who have achieved remission in pars planitis with just NSAID therapy.
new classes of drugs are in the works that might achieve this. Luveniq (formerly known as LX211) is in the approval process and it seems to quell intermediate and posterior uveitis not related to a pathogen. if you have underlying systemic autoimmune disease such as Sarcoidosis, then Methotrexate would be the drug of choice.

Wish you the very best,
Mike

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